Dr Stock Pick HOT News & Alerts!

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FREE Daily Stock Alerts From DrStockPick.com

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Monday Dec. 28, 2009

DrStockPick.com Stock Report!

PWRM, CGEN

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PWRM, Power 3 Medical Products Inc, PWRM.OB

PWRM is a leading bio-medical company engaged in the commercialization of neurodegenerative disease and cancer biomarkers, pathways, and mechanisms of diseases through the development of diagnostic tests and drug targets. PWRM’s patent-pending technologies are being used to develop screening and diagnostic tests for the early detection and prognosis of disease, identify protein biomarkers, and drug targets. Diagnostic tests are targeted toward markets with critical unmet needs in areas including neurodegenerative disease (NuroPro(R)) and breast cancer (BC-SeraPro(TM)). PWRM expects to complete phase II clinical validation trials of its blood serum diagnostics for Alzheimer’s disease (NuroPro-AD), Parkinson’s disease (NuroPro-PD) and breast cancer in 2010, followed by filings with the FDA. Power3 operates a state-of-the-art CLIA certified laboratory in The Woodlands (Houston), Texas. Power3 continues to evolve and enhance its IP portfolio, employing sensitive and specific combinations of biomarkers it has discovered from a broad range of diseases as the basis of highly selective blood-based tests for ALS, Alzheimer’s, and Parkinson’s diseases, and breast cancer.

PWRM reported that the company’s President and CSO, Dr. Ira Goldknopf, delivered an invited Keynote address and chaired a session on “Biomarkers and Diagnostics in Personalized Medicine (Track 6-4),” at the BIT Life Sciences 2nd International Congress and Expo of Molecular Diagnostics in Beijing, China, the past month. The Theme of the meeting was “New Leadership of Personalized Medicine.”

Dr. Goldknopf described the company’s unique ability to employ PWRM’s blood protein biomarkers to differentially diagnose mild Alzheimer’s and Parkinson’s diseases, distinguish between them, distinguish from normal controls, distinguish from patients with Alzheimer’s and Parkinson’s like disorders (disease controls) and distinguish drug naive and drug treated patients. He also presented results for early diagnosis of invasive breast cancer with and without ductal carcinoma in situ, distinguishing between them, distinguishing them from normal and benign controls. The final topic covered was the discovery of biomarkers in bone marrow cells from chronic myelogenous leukemia patients that predict whether they would respond to the drug imatinib mesylate (Gleevec).

“Power3 has begun confidential discussions with a flagship Chinese Biotechnology Company with an eye to co-develop high throughput blood tests for the Chinese market,” said Dr. Goldknopf. “We intend to establish a major worldwide presence.”

More about PWRM at www.power3medical.com

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CGEN, Compugen Ltd.

CGEN is a leading drug and diagnostic product candidate discovery company. Unlike traditional high throughput trial and error experimental based discovery, CGEN’s discovery efforts are based on in silico (by computer) prediction and selection utilizing a growing number of field focused proprietary discovery platforms accurately modeling biological processes at the molecular level.

CGEN announced today the discovery and experimental validation of CGEN-671, a new drug target for multiple epithelial tumors. CGEN-671 is a membrane splice variant of CD55, a known drug target for gastric cancer for which monoclonal antibody (mAb) therapeutics are in clinical development by others. The potential application of CGEN-671 as a drug target was initially predicted in silico by Compugen through the use of its Monoclonal Antibody Targets Discovery Platform; the predicted molecule was then validated experimentally in multiple epithelial tumors. Epithelial tumors, also referred to as carcinomas, account for approximately 85% of all cancers, including the ten most prevalent cancers in the western world, such as breast, colorectal, lung, ovary, prostate and skin. Compugen has filed patent applications covering this novel splice variant and its various therapeutic and diagnostic utilities.

More about CGEN at www.cgen.com.

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Keep a close eye on PWRM and CGEN, do your homework, and like always BE READY for the ACTION!

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